Explain SMBC — the wiki for Saturday Morning Breakfast Cereal

In this comic, a couple is in bed and something has gone wrong with a condom ("It broke?"). The woman suggests the classic IT troubleshooting advice: "Just take it off and put it on again." The caption reads: "Programmers have a high rate of fertility."

The joke is a double-layered pun built on the universal tech support mantra "Have you tried turning it off and on again?" -- a reboot that fixes most computer problems but is completely useless (and in fact counterproductive) when applied to contraception. Taking a broken condom off and putting on a new one after the fact doesn't undo the problem. The caption ties it together by suggesting that programmers, so conditioned to solve every problem by restarting, would apply this instinct in the bedroom with predictable biological consequences. It is a compact joke about how professional habits can become absurd reflexes when applied outside their proper domain.