Explain SMBC — the wiki for Saturday Morning Breakfast Cereal

The comic shows a flat, toad-like creature with small triangular shapes embedded in its back, while a voice from above (implied to be God) exclaims: "Nope. Nope nope nope. That's enough. Evolution is cancelled." The caption reads: "God discovers the Surinam Toad."

The Surinam toad (Pipa pipa) is a real species of aquatic toad native to South America, and it is famous for having one of the most unsettling reproductive methods in the animal kingdom. The female carries her fertilized eggs embedded in the skin of her back, where they develop through the tadpole stage entirely within pockets in her flesh. When the young are ready, they emerge by bursting out through the skin of her back, creating a sight that is deeply disturbing to most humans and a frequent star of "nope" videos on the internet. The comic imagines even God being so horrified by this creature that He wants to shut down the entire evolutionary process. It plays on the common internet reaction of declaring certain animals too creepy to exist, elevated to a cosmic scale.