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Explanation
This is a short, punchy comic that combines the Hardy Boys mystery series with the art of M.C. Escher.
Two characters (styled as the Hardy Boys, the classic young detective duo from the long-running book series) are investigating a piece of furniture. One exclaims: "Ha! Look Frank! Below this drawer's bottom, there's another drawer!" When asked what's in it, the answer is: "The... top of the drawer."
The caption reads: "Tragically, the Hardy Boys never recovered from investigating M.C. Escher's home."
The joke is a riff on Escher's famous impossible geometries -- staircases that loop endlessly, hands drawing themselves, water flowing uphill. In an Escher house, spatial logic breaks down: the bottom of a drawer leads to the top of the same drawer, creating an impossible loop. The Hardy Boys, whose mysteries always have tidy rational solutions, are completely out of their depth in a space where physical reality itself is paradoxical. The word "tragically" in the caption implies they went mad or were forever trapped, adding a darkly comic edge to what is essentially a visual-logic pun.