doom-2
Explanation
The Joke
A cloaked figure (Death/the Grim Reaper) is playing a video game and describes the rules to another character: "I give you two amulets. I cast down drain. Near three skulls appear." The other character says "It's got three skulls? Let me see that." The Grim Reaper continues: "For just one instant, you appear to be recklessly alive, or briefly delighted for one excruciating moment, playing an intricately mad game." The other character responds: "You know what, you can keep it. Look, the scorpion keeps freaking me out." The Reaper shouts "DEATH! DEATH! DEATH!"
The comic plays on the idea of Death trying to get someone interested in a game (likely a tabletop or video game with death-themed imagery), but the person is too put off by the creepy aesthetic to play along. Death gets frustrated that nobody wants to engage with death-themed entertainment.
The Humor
The humor comes from the juxtaposition of Death as an intimidating cosmic force with Death as an enthusiastic but socially awkward gamer who cannot get anyone to play with them. Death's elaborate description of the game mechanics is meant to sound enticing, but the other character is simply creeped out by all the skulls and scorpions. Death's frustrated outburst of "DEATH! DEATH! DEATH!" at the end reads less like a terrifying curse and more like a petulant gamer throwing a tantrum -- undermining the gravitas of the Grim Reaper entirely.