judge
Explanation
This comic tackles the question of why people are judgmental about other people's tastes, particularly what entertainment or media they enjoy.
In the first panel, someone asks why people are so judgmental about others' tastes, to which another character replies "no idea, no way." The comic then escalates through several panels: every single great artistic movement is characterized as essentially being a group of people saying "fuck you" to an existing form of art, declaring that a new paradigm is needed and the old one "must be destroyed." People are described as enjoying things like something being "attractive" and "a pandemic" simultaneously.
The joke builds to its punchline when someone points out "you draw a webcomic about science jokes and wiener jokes," to which the cartoonist character essentially must acknowledge this with "I... man... must eat much." The humor lies in the contrast between the grand narrative of artistic movements being acts of fierce creative rebellion and judgment, and the reality of the cartoonist's own humble creative output. It satirizes the pomposity of treating taste-based judgments as high artistic discourse when most creative work (including SMBC itself) is far more modest in its ambitions. The comic is self-deprecating, with Zach Weinersmith acknowledging that his own work doesn't fit the lofty artistic revolutionary framework he just described.