mans-2
Explanation
The comic shows a spider-themed superhero called "Man-Spider" (a play on Spider-Man). Man-Spider explains that he was bitten by a radioactive man, giving him the powers of a man. In the next panel, a bystander asks "Like what?" and Man-Spider responds "I can feel worries about abstractions!" -- demonstrating his newly acquired human power. The final panel shows a regular spider in a web having an "EPIPHANY" while Man-Spider swings away saying "Wow."
The joke inverts the Spider-Man origin story. Instead of a man gaining spider powers (wall-crawling, web-shooting, spider-sense), a spider gains man powers -- which turn out to be the ability to worry about abstract concepts. This is a wry commentary on the human condition: our defining "superpower" as a species isn't strength or speed but the dubious gift of existential anxiety. The spider's "epiphany" in the final panel suggests the horror of suddenly gaining human-style consciousness -- echoing the common SMBC theme that self-awareness is more curse than blessing.