toxic
Explanation
This comic plays on the disconnect between appreciating nature aesthetically and understanding it scientifically. In the first panels, someone observes "The monarch butterfly is safe to humans" but then adds that if it were toxic, it would make a good model for other butterflies that would want to mimic it -- referencing Batesian mimicry, the real biological phenomenon where harmless species evolve to resemble dangerous ones to deter predators.
The joke escalates when the character says something like "Whenever someone tries to talk to me, I immediately start talking about how nature is full of toxins and deception," explaining that they can't stop themselves from launching into ecological lectures. The punchline in the "Earlier" flashback panel shows someone trying to have a normal pleasant moment observing nature ("Hey, do you come here for the poisonous frogs?") and the character immediately diving into pedantic biological commentary.
The humor satirizes a specific personality type: the person who cannot enjoy nature on a simple aesthetic level without turning every observation into a biology lecture. It's a comic about how scientific knowledge, while valuable, can make someone insufferable in casual social settings. The character has become so consumed by ecological facts about toxicity and mimicry that every interaction with nature becomes a classroom lecture that drives other people away.