adam39s-rib
Explanation
The Joke
The comic reimagines the Biblical story of God creating Eve from Adam's rib. God explains to Adam that he used a rib bone to create woman, which is why women are made of "magical bone" and are therefore "permanently soft everywhere." Adam asks why God told him to never cross a woman, and God explains it is because "since women are made from compressed bone, a single woman battling one hundred men is petrified of armies of planet-sized bone-people." The dialogue is deliberately garbled and nonsensical, treating the rib origin story as if it has absurd physical implications.
The punchline comes in the final panels where God declares that "women are practically unstoppable in combat" and that permanent arms races exist to keep things safe, which is why "women's pants don't have pockets -- to level the playing field." The last panel has God saying he would start tucking his mom in every night, while Adam responds with shock: "You know that? You're outnumbered -- you have to love us all!"
The Humor
The comic satirizes the tendency to derive sweeping, absurd conclusions from the Genesis creation story. By taking the premise that Eve was literally made from a bone and extrapolating it to ridiculous extremes -- women being indestructible bone warriors, the lack of pockets in women's clothing being a deliberate safety measure -- Weinersmith mocks how people sometimes use origin myths to justify modern gender dynamics. The joke about women's pants not having pockets is a nod to a real and well-known complaint, here given the most absurd possible justification.
References
The comic references the Biblical account in Genesis 2:21-22, where God creates Eve from one of Adam's ribs. The "women's pants don't have pockets" joke references the long-standing and widely discussed design choice in women's fashion where pockets are often absent or impractically small compared to men's clothing.